Healthy aquatic ecosystems require clean water but many creeks and streams may be impaired by human activity. This study is focused on surface water quality of the Alplaus and Indian Kill streams located within the Alplaus Watershed in Schenectady and Saratoga Counties (NY). The primary goal of this study is to understand the extent of water quality impairment using a range of indicators to understand the impacts of failing infrastructure and stressors to surface water. Sixty-five water samples were collected in the fall of 2021 from six locations in the Alplaus and Indian Kill and they were taken during low- and high-flow conditions. Samples were measured for fecal indicator bacteria (FIB) Enterococcus, dissolved ions, and physical water quality parameters. At high flow, samples show elevated levels of FIB and phosphate. Single sample Enterococcus levels exceeded the EPA Beach Advisory Value (BAV = 60 mpn/100 ml) in 93% of samples (61/65) from both low- and high-flow conditions.The two highest recorded Enterococcus values were after periods of high rainfall along the Mayfair Creek, a tributary to the Indian Kill in an urban setting. During low flow (or baseflow), high levels of nitrate, sodium, and chloride may indicate input from contaminated groundwater, especially in the urban setting of Glenville (Indian Kill). The Alplaus and Indian Kill streams are fed by groundwater discharge during low flow, indicating there is contamination of the groundwater. Low-flow concentrations of chloride and nitrate were three and four times higher than high flow in the Alplaus Watershed respectively. Through increased urbanization and aging infrastructure, it appears that surface water quality in streams and rivers has been impaired with sewage from leaky pipes or failing septic systems and chemical pollutants such as road salt. Local areas with chronic contamination have a large number of septic systems, most presumably 60-70 yr old, and are a likely suspect of water quality impairment to groundwater that is especially apparent in the Indian Kill.