This thesis aims to build upon the Solow growth model to find the causes of Singapore’s rapid economic growth and transformation from 1965 to 2021. The basic Solow Growth model factors capital and labor force as the inputs for economic growth. However, the assumptions of this model are too narrow, as there are other factors behind a country’s economic growth. Existing literature on Singapore’s economic growth has showcased the various factors behind such growth. Natural resources, human capital, technology, trade, FDI (Foreign Direct Investment), governance and leadership, political stability, location, culture, and geopolitics have major roles in Singapore’s economic growth and the Singaporean economy. These determinants can be cataloged into qualitative factors and quantitative factors. Hence, the thesis will take two different approaches. First, the thesis will provide an empirical framework, a regression analysis, to measure the effects of the determinants on real GDP growth. Second, the thesis will provide a qualitative assessment of the determinants through a case study. Singapore’s statehood and economic development were historically unprecedented. Thus, a case study approach is required to understand the context of Singapore’s economic growth. The case study will involve qualitative factors such as geography, politics, leadership, governance, and culture. Furthermore, the roles of economic policies, immigration policies, FDI, manufacturing, trade, financial sector, and ICT (Information and Communication Technology) will be thoroughly discussed. The results of the study aim to provide comprehensive empirical and case study evidence to highlight the determinants of Singapore’s economic growth from 1965 to 2021.